Uruguay bowed out of the World Cup as goalkeeper Fernando Muslera’s howler gifted Spain a 1-0 win in Guadalajara to secure top spot in Group H.
Alex Baena’s weak shot slipped through Muslera’s grasp for the only goal as Spain avoided a last-32 showdown against Argentina.
The European champions will instead face Austria or Algeria next in Los Angeles on Thursday.
Uruguay’s defeat allowed debutants Cape Verde to secure second place and a meeting with Lionel Messi and the defending champions thanks to a 0-0 draw against Saudi Arabia.
Two-time winners Uruguay become the highest ranked side to crash out in the group stages as the defeat rounded off a miserable tournament for Marcelo Bielsa and his squad.
After draws against Cape Verde and Saudi Arabia, reports of a revolt in the Uruguay camp emerged with leading players, including Real Madrid’s Federico Valverde, clashing with Bielsa over his tactics.
Bielsa controversially substituted Valverde on the hour mark and said the decision to replace Muslera at half-time had been taken by the player himself.